SARS-CoV-2 Infection in Infants Less than 90 Days Old

Leena B Mithal; Kerri Z Machut; William J Muller; Larry K Kociolek

doi:10.1016/j.jpeds.2020.06.047

SARS-CoV-2 Infection in Infants Less than 90 Days Old

J Pediatr. 2020 Sep:224:150-152. doi: 10.1016/j.jpeds.2020.06.047. Epub 2020 Jun 18.

Authors

Leena B Mithal¹, Kerri Z Machut², William J Muller³, Larry K Kociolek³

Affiliations

¹ Division of Infectious Diseases, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago and Feinberg School of Medicine, Northwestern University, Chicago, IL. Electronic address: lmithal@luriechildrens.org.
² Division of Neonatology, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago and Feinberg School of Medicine, Northwestern University, Chicago, IL.
³ Division of Infectious Diseases, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago and Feinberg School of Medicine, Northwestern University, Chicago, IL.

Abstract

This is a single-center US case series of 18 infants <90 days old who tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These infants had a mild febrile illness without significant pulmonary disease. One-half of the infants were hospitalized; 1 had bacterial urinary tract co-infection. Nasopharyngeal viral loads were notably high. Latinx ethnicity was overrepresented.

Keywords: COVID-19; neonate.

MeSH terms

Betacoronavirus
COVID-19
COVID-19 Testing
Chicago
Clinical Laboratory Techniques
Coronavirus Infections / diagnosis*
Female
Fever / diagnosis*
Fever / virology
Hospitalization
Humans
Infant
Male
Pandemics
Patient Admission
Pneumonia, Viral / diagnosis*
Reverse Transcriptase Polymerase Chain Reaction
SARS-CoV-2
Serologic Tests
Urinary Tract Infections / complications
Urinary Tract Infections / microbiology
Viral Load