User profiles for "author:Ankur Sharma"

Ankur Sharma

- Verified email at perkins.org.au - Cited by 1660

Dr. Ankur Sharma

- Verified email at snowflake.com - Cited by 365

Dr Ankur Sharma

- Verified email at strath.ac.uk - Cited by 356

Oncofetal reprogramming in tumour development and progression

A Sharma, C Blériot, J Currenti, F Ginhoux - Nature Reviews Cancer, 2022 - nature.com
Embryonic development is characterized by rapidly dividing cells, cellular plasticity and a
highly vascular microenvironment. These features are similar to those of tumour tissue, in …

Review of guidelines and recommendations from 17 countries highlights the challenges that clinicians face caring for neonates born to mothers with COVID‐19

KT Yeo, JL Oei, D De Luca, GM Schmölzer… - Acta …, 2020 - Wiley Online Library
Aim This review examined how applicable national and regional clinical practice guidelines
and recommendations for managing neonates born to mothers with COVID‐19 mothers …

[HTML][HTML] Cyclodextrin-based dermatological formulations: Dermopharmaceutical and cosmetic applications

L Ferreira, F Mascarenhas-Melo, S Rabaça… - Colloids and Surfaces B …, 2023 - Elsevier
The progress in new delivery systems for active ingredients has boosted the
dermopharmaceutical and cosmetic fields by allowing formulations to display enhanced skin …

[HTML][HTML] Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease

K Mulder, AA Patel, WT Kong, C Piot, E Halitzki… - Immunity, 2021 - cell.com
Mononuclear phagocytes (MNPs) encompass dendritic cells, monocytes, and macrophages
(MoMac), which exhibit antimicrobial, homeostatic, and immunoregulatory functions. We …

[PDF][PDF] Onco-fetal reprogramming of endothelial cells drives immunosuppressive macrophages in hepatocellular carcinoma

A Sharma, JJW Seow, CA Dutertre, R Pai, C Blériot… - Cell, 2020 - cell.com
We employed scRNA sequencing to extensively characterize the cellular landscape of
human liver from development to disease. Analysis of∼ 212,000 cells representing human …

Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models

AA Cohen, N van Doremalen, AJ Greaney, H Andersen… - Science, 2022 - science.org
To combat future severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health …

Taurine deficiency as a driver of aging

P Singh, K Gollapalli, S Mangiola, D Schranner… - Science, 2023 - science.org
Aging is associated with changes in circulating levels of various molecules, some of which
remain undefined. We find that concentrations of circulating taurine decline with aging in …

[HTML][HTML] The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

A Sharma, WS Yeow, A Ertel, I Coleman… - The Journal of …, 2010 - Am Soc Clin Investig
Retinoblastoma (RB; encoded by RB1) is a tumor suppressor that is frequently disrupted in
tumorigenesis and acts in multiple cell types to suppress cell cycle progression. The role of …

[PDF][PDF] Microbial exposure during early human development primes fetal immune cells

A Mishra, GC Lai, LJ Yao, TT Aung, N Shental… - Cell, 2021 - cell.com
The human fetal immune system begins to develop early during gestation; however, factors
responsible for fetal immune-priming remain elusive. We explored potential exposure to …

[HTML][HTML] A subset of Kupffer cells regulates metabolism through the expression of CD36

C Blériot, E Barreby, G Dunsmore, R Ballaire… - Immunity, 2021 - cell.com
Tissue macrophages are immune cells whose phenotypes and functions are dictated by
origin and niches. However, tissues are complex environments, and macrophage …