Background Low‐back pain with leg pain (sciatica) may be caused by a herniated
intervertebral disc exerting pressure on the nerve root. Most patients will respond to …

Objective. To identify a critical appraisal tool for clinical practice guidelines that could serve
as a basis for the development of an appraisal tool for clinical pathways. Design. Systematic …

Introduction Many national guidelines concerning the management of ovarian cancer
currently advocate the risk of malignancy index (RMI) to characterise ovarian pathology …

BACKGROUND: Early identification of alcohol abuse or dependence is important in general
practice because many diseases are influenced by alcohol. General practitioners, however …

Background: The lack of a clear definition of the palliative care patient hampers the
comparison of results across different studies and impedes implementation of research …

Clinical question What is the role of medical cannabis or cannabinoids for people living with
chronic pain due to cancer or non-cancer causes? Current practice Chronic pain is common …

Background Serious infections in children (sepsis, meningitis, pneumonia, pyelonephritis,
osteomyelitis, and cellulitis) are associated with considerable mortality and morbidity. In …

OBJECTIVE: To perform a meta-analysis to assess diagnostic characteristics of the CAGE in
screening for alcohol abuse or dependence in a general clinical population and to test a …

Background Prompt diagnosis of acute myocardial infarction or acute coronary syndrome is
very important. Aim A systematic review was conducted to determine the accuracy of 10 …

Background: Multi-morbidity and polypharmacy of the elderly population enhances the
probability of elderly in residential long-term care facilities experiencing inappropriate …