Importance Chronic fatigue syndrome (CFS) is a disabling condition with unknown disease
mechanisms and few treatment options. Objective To explore the pathophysiology of CFS …

Background Chronic fatigue syndrome (CFS) is a prevalent and disabling condition affecting
adolescents. The pathophysiology is poorly understood, but immune alterations might be an …

Aim To study health related quality of life (HRQOL) and depressive symptoms in adolescents
with chronic fatigue syndrome (CFS) and to investigate in which domains their HRQOL and …

Objective To compare cognitive function in adolescents with chronic fatigue with cognitive
function in healthy controls (HC). Study design Cross-sectional study. Setting Paediatric …

Objectives Although pain is a significant symptom in chronic fatigue syndrome (CFS), pain is
poorly understood in adolescents with CFS. The aim of this study was to explore pain …

Background Chronic fatigue syndrome (CFS) is a common and disabling disorder, and a
major threat against adolescent health. The pathophysiology is unknown, but alteration of …

Chronic fatigue syndrome (CFS) is characterized by long‐lasting, disabling and unexplained
fatigue that is often accompanied by unrefreshing sleep. The aim of this cross‐sectional …

Chronic fatigue syndrome (CFS) is a prevalent and disabling condition among adolescents.
The pathophysiology is poorly understood, but low-grade systemic inflammation has been …

Clonidine, an α2-adrenergic receptor agonist, decreases circulating norepinephrine and
epinephrine, attenuating sympathetic activity. Although catechol-O-methyltransferase …

Abstract Aim The 2003 Canadian Consensus Criteria for chronic fatigue syndrome (CFS)
are often assumed to suggest low‐grade systemic inflammation, but have never been …