Abstract Definition: ECLAMC ('Estudio Colaborativo Latino Americano de Malformaciones
Congénitas') is a program for the clinical and epidemiological investigation of risk factors in …

Sirenomelia is a very rare limb anomaly in which the normally paired lower limbs are
replaced by a single midline limb. This study describes the prevalence, associated …

The wide variation in cerebral and facial phenotypes and the recognized etiologic
heterogeneity of holoprosencephaly (HPE) contribute to the observed inter‐study …

Background Cleft lip or palate (or the two in combination) is a common birth defect that
results from a mixture of genetic and environmental factors. We searched for a specific …

Nonsyndromic or isolated cleft lip with or without cleft palate (CL/P) occurs in wide
geographic distribution with an average birth prevalence of 1/700. We used direct …

Orofacial clefts (OFCs), which include non-syndromic cleft lip with or without cleft palate
(CL/P), are among the most common birth defects in humans, affecting approximately 1 in …

To verify whether the decreasing neural tube defects birth prevalence rates in Chile are due
to folic acid fortification or to pre‐existing decreasing trends, we performed a population …

Gastroschisis offers the intriguing epidemiological situation of a pandemic, strongly
associated with very low maternal age. Identifying gastroschisis, and distinguishing it from …

Nonsyndromic orofacial clefts (OFCs) are a heterogeneous group of common craniofacial
birth defects with complex etiologies that include genetic and environmental risk factors …

Cleft palate (CP) is a common birth defect occurring in 1 in 2,500 live births. Approximately
half of infants with CP have a syndromic form, exhibiting other physical and cognitive …