User profiles for "author:James Fitzpatrick"
James FitzpatrickGlobal Head, Scientific Operations pRED 360 Labs, Roche Verified email at roche.com Cited by 10218 |
Proposal for a pathogenesis‐based classification of tumoral calcinosis
DP Smack, SA Norton… - International journal of …, 1996 - Wiley Online Library
Background. Deposition of calcium in skin is currently categorized into a group of disorders
referred to as calcinosis cutis. Divisions between types and subtypes within this confusing …
referred to as calcinosis cutis. Divisions between types and subtypes within this confusing …
Modern laser scanning confocal microscopy
PO Bayguinov, DM Oakley, CC Shih… - Current protocols in …, 2018 - Wiley Online Library
Since its commercialization in the late 1980's, confocal laser scanning microscopy (CLSM)
has since become one of the most prevalent fluorescence microscopy techniques for three …
has since become one of the most prevalent fluorescence microscopy techniques for three …
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
DF Egan, DB Shackelford, MM Mihaylova, S Gelino… - Science, 2011 - science.org
Adenosine monophosphate–activated protein kinase (AMPK) is a conserved sensor of
intracellular energy activated in response to low nutrient availability and environmental …
intracellular energy activated in response to low nutrient availability and environmental …
[PDF][PDF] Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet
While diet-induced obesity has been exclusively attributed to increased caloric intake from
fat, animals fed a high-fat diet (HFD) ad libitum (ad lib) eat frequently throughout day and …
fat, animals fed a high-fat diet (HFD) ad libitum (ad lib) eat frequently throughout day and …
Completely regressed primary cutaneous malignant melanoma with nodal and/or visceral metastases: a report of 5 cases and assessment of the literature and …
WA High, D Stewart, CRH Wilbers, CJ Cockerell… - Journal of the American …, 2005 - Elsevier
BACKGROUND: Partial regression of primary cutaneous malignant melanoma is not
uncommon and may predict a higher likelihood of metastasis and decreased survival …
uncommon and may predict a higher likelihood of metastasis and decreased survival …
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders
INTRODUCTION The meninges are a three-layer membrane that covers the central nervous
system (CNS): The outermost layer, the dura mater, is attached onto the skull periosteum; …
system (CNS): The outermost layer, the dura mater, is attached onto the skull periosteum; …
[HTML][HTML] Functional characterization of the dural sinuses as a neuroimmune interface
Despite the established dogma of central nervous system (CNS) immune privilege,
neuroimmune interactions play an active role in diverse neurological disorders. However …
neuroimmune interactions play an active role in diverse neurological disorders. However …
Sentinel lymph node imaging using quantum dots in mouse tumor models
B Ballou, LA Ernst, S Andreko, T Harper… - Bioconjugate …, 2007 - ACS Publications
We demonstrate that quantum dots injected into two model tumors rapidly migrate to sentinel
lymph nodes. PEG-coated quantum dots having terminal carboxyl, amino, or methoxyl …
lymph nodes. PEG-coated quantum dots having terminal carboxyl, amino, or methoxyl …
Fluorogen-activating single-chain antibodies for imaging cell surface proteins
C Szent-Gyorgyi, BF Schmidt, Y Creeger… - Nature …, 2008 - nature.com
Imaging of live cells has been revolutionized by genetically encoded fluorescent probes,
most famously green and other fluorescent proteins, but also peptide tags that bind …
most famously green and other fluorescent proteins, but also peptide tags that bind …
SARS-CoV-2 infects human engineered heart tissues and models COVID-19 myocarditis
AL Bailey, O Dmytrenko, L Greenberg… - Basic to Translational …, 2021 - jacc.org
There is ongoing debate as to whether cardiac complications of coronavirus disease-2019
(COVID-19) result from myocardial viral infection or are secondary to systemic inflammation …
(COVID-19) result from myocardial viral infection or are secondary to systemic inflammation …