In normal vascular physiology, NO plays a key role to maintain the vascular wall in a
quiescent state by inhibition of inflammation, cellular proliferation, and thrombosis. This is in …

Dysfunction of the vascular endothelium is a hallmark of most conditions that are associated
with atherosclerosis and is therefore held to be an early feature in atherogenesis. However …

The discovery of nitric oxide (NO) as a crucial endothe-lium-derived molecule for vascular
relaxation and the recognition of the endothelium as more than a passive interface between …

The content of these European Society of Cardiology (ESC) Guidelines has been published
for personal and educational use only. No commercial use is authorized. No part of the ESC …

Endothelial function is thought to be an important factor in the pathogenesis of
atherosclerosis, hypertension and heart failure. In the 1990s, high-frequency …

Background The associations of blood pressure with the different manifestations of incident
cardiovascular disease in a contemporary population have not been compared. In this study …

Background Semaglutide, a glucagon-like peptide-1 receptor agonist, has been shown to
reduce the risk of adverse cardiovascular events in patients with diabetes. Whether …

Objectives. This study attempted to assess whether coronary risk factors are associated with
endothelial dysfunction in the systemic arteries of asymptomatic men and women …

Objectives. This study assessed whether aging is associated with progressive endothelial
dysfunction, whether the pattern of any age-related decline in vascular health is different in …

Background Systemic inflammation may impair vascular function, and epidemiologic data
suggest a possible link between periodontitis and cardiovascular disease. Methods We …