Pharmacological considerations for tenofovir and emtricitabine to prevent HIV infection
PL Anderson, JJ Kiser, EM Gardner… - Journal of …, 2011 - academic.oup.com
The use of antiretroviral medications in HIV-negative individuals as pre-exposure
prophylaxis (PrEP) is a promising approach to prevent HIV infection. Tenofovir disoproxil …
prophylaxis (PrEP) is a promising approach to prevent HIV infection. Tenofovir disoproxil …
Tenofovir, emtricitabine, and tenofovir diphosphate in dried blood spots for determining recent and cumulative drug exposure
JR Castillo-Mancilla, JH Zheng, JE Rower… - AIDS research and …, 2013 - liebertpub.com
Tenofovir (TFV) disoproxil fumarate (TDF)±emtricitabine (FTC) are widely used for HIV
treatment and chemoprophylaxis, but variable adherence may lead to suboptimal …
treatment and chemoprophylaxis, but variable adherence may lead to suboptimal …
Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC–MS/MS detection
An ultra-sensitive liquid chromatography tandem mass spectrometry (LC–MS/MS) assay
was developed and validated to facilitate the assessment of clinical pharmacokinetics of …
was developed and validated to facilitate the assessment of clinical pharmacokinetics of …
[HTML][HTML] Evaluation of sulfobutylether-β-cyclodextrin (SBECD) accumulation and voriconazole pharmacokinetics in critically ill patients undergoing continuous renal …
Introduction Intravenous (IV) voriconazole is not recommended in patients with creatinine
clearance< 50 ml/min to avoid potentially toxic accumulation of sulfobutylether-β …
clearance< 50 ml/min to avoid potentially toxic accumulation of sulfobutylether-β …
Intracellular tenofovir and emtricitabine anabolites in genital, rectal, and blood compartments from first dose to steady state
SM Seifert, X Chen, AL Meditz… - AIDS research and …, 2016 - liebertpub.com
The pharmacokinetics (PK) of tenofovir-diphosphate (TFV-DP) and emtricitabine-
triphosphate (FTC-TP), the active anabolites of tenofovir disoproxil fumarate (TDF), and …
triphosphate (FTC-TP), the active anabolites of tenofovir disoproxil fumarate (TDF), and …
Optimizing the use of intravenous magnesium sulfate for acute asthma treatment in children
Background Asthma is the most common pediatric chronic disease and currently affects 7.1
million children in the United States. Many children experience acute asthma exacerbations …
million children in the United States. Many children experience acute asthma exacerbations …
Pharmacodynamic studies of voriconazole: informing the clinical management of invasive fungal infections
KM Job, J Olson, C Stockmann… - Expert review of anti …, 2016 - Taylor & Francis
Introduction: Voriconazole is a broad-spectrum antifungal agent commonly used to treat
invasive fungal infections (IFI), including aspergillosis, candidiasis, Scedosporium infection …
invasive fungal infections (IFI), including aspergillosis, candidiasis, Scedosporium infection …
[HTML][HTML] Zidovudine and lamivudine for HIV infection
PL Anderson, JE Rower - Clinical medicine reviews in therapeutics, 2010 - ncbi.nlm.nih.gov
Zidovudine and lamivudine (ZDV and 3TC) are long-standing nucleoside analog-reverse
transcriptase inhibitors (NRTIs) with extensive clinical experience in a wide spectrum of …
transcriptase inhibitors (NRTIs) with extensive clinical experience in a wide spectrum of …
A population pharmacokinetic-pharmacogenetic analysis of atazanavir
DA Kile, S MaWhinney, CL Aquilante… - AIDS research and …, 2012 - liebertpub.com
Atazanavir is a first-line HIV protease inhibitor commonly co-dosed with ritonavir. Ritonavir
inhibits atazanavir metabolism, decreasing variability and increasing plasma concentrations …
inhibits atazanavir metabolism, decreasing variability and increasing plasma concentrations …
Impact of the CYP2C8 *3 polymorphism on the drug–drug interaction between gemfibrozil and pioglitazone
CL Aquilante, LA Kosmiski, DWA Bourne… - British journal of …, 2013 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• A drug–drug interaction exists
between gemfibrozil (CYP2C8 inhibitor) and pioglitazone (CYP2C8 substrate), whereby …
between gemfibrozil (CYP2C8 inhibitor) and pioglitazone (CYP2C8 substrate), whereby …