[HTML][HTML] Risk and protective factors for child development: An observational South African birth cohort
Background Approximately 250 million (43%) children under the age of 5 years in low-and
middle-income countries (LMICs) are failing to meet their developmental potential. Risk …
middle-income countries (LMICs) are failing to meet their developmental potential. Risk …
[HTML][HTML] Drakenstein Child Health Study (DCHS): investigating determinants of early child development and cognition
Discussion Children in the DCHS develop in a context typical of many communities in South
Africa and other LMICs. There is a critical need for research in LMICs to elucidate underlying …
Africa and other LMICs. There is a critical need for research in LMICs to elucidate underlying …
[HTML][HTML] In-utero exposure to indoor air pollution or tobacco smoke and cognitive development in a South African birth cohort study
Abstract Background and Aims There is increasing evidence indicating that air pollution
exposure is associated with neuronal damage. Since pregnancy is a critical window of …
exposure is associated with neuronal damage. Since pregnancy is a critical window of …
[HTML][HTML] Maternal psychosocial risk factors and child gestational epigenetic age in a South African birth cohort study
Accelerated epigenetic aging relative to chronological age has been found to be associated
with higher risk of mortality in adults. However, little is known about whether and how in …
with higher risk of mortality in adults. However, little is known about whether and how in …
Effect of hazardous alcohol use during pregnancy on growth outcomes at birth: findings from a South African cohort study
Background Cohort studies have noted associations between hazardous alcohol use during
pregnancy and infant growth outcomes, but many have not controlled for potential …
pregnancy and infant growth outcomes, but many have not controlled for potential …
[HTML][HTML] Antenatal maternal depression, early life inflammation and neurodevelopment in a South African birth cohort
PJW Naudé, C Pariante, N Hoffman… - Brain, Behavior, and …, 2022 - Elsevier
Background Antenatal exposure to maternal psychological adversity, including depression,
increases the risk of impaired neurodevelopment in children. The underlying biological …
increases the risk of impaired neurodevelopment in children. The underlying biological …
[HTML][HTML] Maternal perinatal depression and child brain structure at 2-3 years in a South African birth cohort study
Maternal perinatal depression is associated with risk of adverse child developmental
outcomes and differences in offspring brain structure. Evidence from low-and middle-income …
outcomes and differences in offspring brain structure. Evidence from low-and middle-income …
Association of maternal and child anemia with brain structure in early life in South Africa
Importance Anemia affects millions of pregnant women and their children worldwide,
particularly in low-and middle-income countries. Although anemia in pregnancy is a well …
particularly in low-and middle-income countries. Although anemia in pregnancy is a well …
Influence of Maternal Childhood Trauma on Perinatal Depression, Observed Mother–Infant Interactions, and Child Growth
Introduction Mothers who have experienced childhood trauma may be at increased risk for
disruptions in caregiving behavior, with potential consequences for early child development …
disruptions in caregiving behavior, with potential consequences for early child development …
[HTML][HTML] DNA methylation as a potential mediator of the association between indoor air pollution and neurodevelopmental delay in a South African birth cohort
D Feil, S Abrishamcar, GM Christensen, A Vanker… - Clinical …, 2023 - Springer
Background Exposure to indoor air pollution during pregnancy has been linked to
neurodevelopmental delay in toddlers. Epigenetic modification, particularly DNA methylation …
neurodevelopmental delay in toddlers. Epigenetic modification, particularly DNA methylation …