User profiles for "author:Niamh O' Brien"

Niamh Louise O'Brien

Postdoctoral Research Associate
Verified email at kcl.ac.uk
Cited by 2917

Sensitivity to reward and punishment in eating disorders

A Harrison, N O'Brien, C Lopez, J Treasure - Psychiatry research, 2010 - Elsevier
The aim of this review was to collate and summarise the self-report data regarding
anomalies in sensitivity to reward and punishment in eating disorders (ED) with use of a …

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

N Mullins, AJ Forstner, KS O'Connell, B Coombes… - Nature …, 2021 - nature.com
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …

Rare coding variants in ten genes confer substantial risk for schizophrenia

T Singh, T Poterba, D Curtis, H Akil, M Al Eissa… - Nature, 2022 - nature.com
Rare coding variation has historically provided the most direct connections between gene
function and disease pathogenesis. By meta-analysing the whole exomes of 24,248 …

So round the spiral again: A reflective participatory research project with children and young people

N O'Brien, T Moules - Educational Action Research, 2007 - Taylor & Francis
Historically the voices of children in research have been silent. They are often seen as
victims or beneficiaries of research rather than co‐researchers or partners. This is beginning …

Implications for European Physical Education Teacher Education during the COVID-19 pandemic: a cross-institutional SWOT analysis

W O'Brien, M Adamakis, N O'Brien… - European Journal of …, 2020 - Taylor & Francis
The present study, using a sample of Physical Education Teacher Education (PETE)
representatives from five Higher Education European institutions (England, Finland, Greece …

[PDF][PDF] A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder

J Duan, J Shi, A Fiorentino, C Leites, X Chen… - The American Journal of …, 2014 - cell.com
Schizophrenia (SZ) genome-wide association studies (GWASs) have identified common risk
variants in> 100 susceptibility loci; however, the contribution of rare variants at these loci …

[HTML][HTML] Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

I Alić, PA Goh, A Murray, E Portelius, E Gkanatsiou… - Molecular …, 2021 - nature.com
A population of more than six million people worldwide at high risk of Alzheimer's disease
(AD) are those with Down Syndrome (DS, caused by trisomy 21 (T21)), 70% of whom …

Modeling Down syndrome in cells: From stem cells to organoids

G Gough, NL O'Brien, I Alic, PA Goh, YJ Yeap… - Progress in Brain …, 2020 - Elsevier
Down Syndrome (DS) is a complex chromosomal disorder, with neurological issues,
featuring among the symptoms. Primary neuronal cells and tissues are extremely useful, but …

Physical education student teachers' wellbeing during Covid-19: Resilience resources and challenges from school placement

N O'Brien, W O'Brien, J Costa… - European Physical …, 2022 - journals.sagepub.com
The coronavirus 2019 (Covid-19) pandemic has given rise to significant global challenges
across education, and specifically in the physical education teacher education (PETE) …

Not sticks and stones but tweets and texts: Findings from a national cyberbullying project

N O'Brien, T Moules - Pastoral care in education, 2013 - Taylor & Francis
This paper presents key findings from a project commissioned by a group of young people to
explore issues related to cyberbullying with 12–18-year olds. In particular, the paper focuses …