[HTML][HTML] Variation in antibiotic prescription rates in febrile children presenting to emergency departments across Europe (MOFICHE): a multicentre observational study

NN Hagedoorn, DM Borensztajn, R Nijman… - PLoS …, 2020 - journals.plos.org
Background The prescription rate of antibiotics is high for febrile children visiting the
emergency department (ED), contributing to antimicrobial resistance. Large studies at …

Global distribution of Leptospira serovar isolations and detections from animal host species: A systematic review and online database

NN Hagedoorn, MJ Maze, M Carugati… - Tropical Medicine & …, 2024 - Wiley Online Library
Objectives Leptospira, the spirochaete causing leptospirosis, can be classified into> 250
antigenically distinct serovars. Although knowledge of the animal host species and …

[HTML][HTML] Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study

P Shah, M Voice, L Calvo-Bado… - The Lancet Regional …, 2023 - thelancet.com
Background The PERFORM study aimed to understand causes of febrile childhood illness
by comparing molecular pathogen detection with current clinical practice. Methods Febrile …

[HTML][HTML] A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children …

HR Jackson, J Zandstra, S Menikou… - The Lancet Digital …, 2023 - thelancet.com
Background Differentiating between self-resolving viral infections and bacterial infections in
children who are febrile is a common challenge, causing difficulties in identifying which …

Prevalence and distribution of non-typhoidal Salmonella enterica serogroups and serovars isolated from normally sterile sites: A global systematic review

NN Hagedoorn, S Murthy, M Birkhold… - Epidemiology & …, 2023 - cambridge.org
To inform coverage by potential vaccines, we aimed to systematically review evidence on
the prevalence and distribution of non-typhoidal Salmonella enterica serogroups and …

[HTML][HTML] A comparison of clinical paediatric guidelines for hypotension with population-based lower centiles: a systematic review

NN Hagedoorn, JM Zachariasse, HA Moll - Critical Care, 2019 - Springer
Background Different definitions exist for hypotension in children. In this study, we aim to
identify evidence-based reference values for low blood pressure and to compare these with …

Development and validation of a prediction model for invasive bacterial infections in febrile children at European Emergency Departments: MOFICHE, a prospective …

NN Hagedoorn, D Borensztajn, RG Nijman… - Archives of disease in …, 2021 - adc.bmj.com
Objectives To develop and cross-validate a multivariable clinical prediction model to identify
invasive bacterial infections (IBI) and to identify patient groups who might benefit from new …

[HTML][HTML] Diversity in the emergency care for febrile children in Europe: a questionnaire study

D Borensztajn, S Yeung, NN Hagedoorn… - BMJ paediatrics …, 2019 - ncbi.nlm.nih.gov
Original article: Diversity in the emergency care for febrile children in Europe: a questionnaire
study - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

[HTML][HTML] Variation in hospital admission in febrile children evaluated at the Emergency Department (ED) in Europe: PERFORM, a multicentre prospective observational …

DM Borensztajn, NN Hagedoorn, I Rivero Calle… - PLoS …, 2021 - journals.plos.org
Objectives Hospitalisation is frequently used as a marker of disease severity in
observational Emergency Department (ED) studies. The comparison of ED admission rates …

Rapid viral testing and antibiotic prescription in febrile children with respiratory symptoms visiting emergency departments in Europe

CD Tan, NN Hagedoorn, JE Dewez… - The Pediatric …, 2022 - journals.lww.com
Background. Inappropriate antibiotic prescribing often occurs in children with self-limiting
respiratory tract infections, contributing to antimicrobial resistance. It has been suggested …