User profiles for "author:Sean Zheng"
 | Sean ZhengImperial College London Verified email at nhs.net Cited by 1501 |
Association of aspirin use for primary prevention with cardiovascular events and bleeding events: a systematic review and meta-analysis
SL Zheng, AJ Roddick - Jama, 2019 - jamanetwork.com
Importance The role for aspirin in cardiovascular primary prevention remains controversial,
with potential benefits limited by an increased bleeding risk. Objective To assess the …
with potential benefits limited by an increased bleeding risk. Objective To assess the …
Association between use of sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide 1 agonists, and dipeptidyl peptidase 4 inhibitors with all-cause mortality …
Importance The comparative clinical efficacy of sodium-glucose cotransporter 2 (SGLT-2)
inhibitors, glucagon-like peptide 1 (GLP-1) agonists, and dipeptidyl peptidase 4 (DPP-4) …
inhibitors, glucagon-like peptide 1 (GLP-1) agonists, and dipeptidyl peptidase 4 (DPP-4) …
Drug treatment effects on outcomes in heart failure with preserved ejection fraction: a systematic review and meta-analysis
Background Clinical drug trials in patients with heart failure and preserved ejection fraction
have failed to demonstrate improvements in mortality. Methods We systematically searched …
have failed to demonstrate improvements in mortality. Methods We systematically searched …
Implantable cardioverter defibrillators for primary prevention of death in left ventricular dysfunction with and without ischaemic heart disease: a meta-analysis of 8567 …
Aims Primary prevention implantable cardioverter defibrillators (ICDs) are established
therapy for reducing mortality in patients with left ventricular systolic dysfunction and …
therapy for reducing mortality in patients with left ventricular systolic dysfunction and …
Phenotypic expression and outcomes in individuals with rare genetic variants of hypertrophic cardiomyopathy
Background Hypertrophic cardiomyopathy (HCM) is caused by rare variants in sarcomere-
encoding genes, but little is known about the clinical significance of these variants in the …
encoding genes, but little is known about the clinical significance of these variants in the …
[HTML][HTML] Correspondence on “ACMG SF v3. 0 list for reporting of secondary findings in clinical exome and genome sequencing: a policy statement of the American …
We were interested to read the recent update on recommendations for reporting of
secondary findings in clinical sequencing 1 and the accompanying updated list of genes in …
secondary findings in clinical sequencing 1 and the accompanying updated list of genes in …
Genetic disorders of surfactant protein dysfunction: when to consider and how to investigate
Genetic mutations affecting proteins required for normal surfactant protein function are a rare
cause of respiratory disease. The genes identified that cause respiratory disease are …
cause of respiratory disease. The genes identified that cause respiratory disease are …
Genotype-Phenotype Taxonomy of Hypertrophic Cardiomyopathy
L Curran, A de Marvao, P Inglese… - Circulation: Genomic …, 2023 - Am Heart Assoc
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is an important cause of sudden
cardiac death associated with heterogeneous phenotypes, but there is no systematic …
cardiac death associated with heterogeneous phenotypes, but there is no systematic …
[HTML][HTML] Heart failure—potential new targets for therapy
A Nabeebaccus, S Zheng, AM Shah - British medical bulletin, 2016 - ncbi.nlm.nih.gov
Introduction/background: Heart failure is a major cause of cardiovascular morbidity and
mortality. This review covers current heart failure treatment guidelines, emerging therapies …
mortality. This review covers current heart failure treatment guidelines, emerging therapies …
Assessing the association between genetic and phenotypic features of dilated cardiomyopathy and outcome in patients with coronary artery disease
RE Jones, DJ Hammersley, S Zheng… - European Journal of …, 2024 - Wiley Online Library
Aims To examine the relevance of genetic and cardiovascular magnetic resonance (CMR)
features of dilated cardiomyopathy (DCM) in individuals with coronary artery disease (CAD) …
features of dilated cardiomyopathy (DCM) in individuals with coronary artery disease (CAD) …