Importance Evidence that longer-term and exclusive breastfeeding reduces child obesity risk
is based on observational studies that are prone to confounding. Objective To investigate …

Background—The duration and exclusivity of breastfeeding in infancy have been inversely
associated with future cardiometabolic risk. We investigated the effects of an experimental …

Alginate‐encapsulated HepG2 cells cultured in microgravity have the potential to serve as
the cellular component of a bioartificial liver. This study investigates their performance in …

Aims To assess the role of brain natriuretic peptide (BNP) in both the acute and chronic
settings in children with left ventricular (LV) failure. Methods and results We undertook a …

Clinical and biochemical features of transient hyperphosphatasemia of infancy and early
childhood are reviewed in 21 patients we have studied and in a further 93 cases reported in …

Simple Summary Novel therapeutic modalities using medical devices have the potential to
deliver effective treatment against the most aggressive form of primary brain tumour …

Objectives This paper reports early screening results from the newborn sickle cell disease
screening programme recently implemented in England. Setting England. Screening is …

We describe two new methods for the separation and quantification of the bone and liver
isoenzymes of alkaline phosphatase (EC 3.1. 3.1) in plasma. In the first, we use wheat-germ …

A test kit (Iso-ALP, Boehringer Mannheim) for measuring human bone alkaline phosphatase
activity in serum or plasma was evaluated in five laboratories in three countries. The assay is …

Background In large-scale epidemiology, bloodspot sampling by fingerstick onto filter paper
has many advantages, including ease and low costs of collection, processing and transport …